Immunoglobulin A (IgA) Syndrome Center

 

IgA nephropathy is a chronic kidney disease that may progress over a period of 10 to 20 years and can lead to end-stage renal disease. It is caused by deposits of the protein immunoglobulin A (IgA) inside the glomeruli (filters) within the kidney. These glomeruli normally filter waste and excess water from the blood and send them to the bladder as urine. However, the IgA protein prevents this filtering process. This may lead to the following:

  • Blood and protein in the urine
  • Swelling in the hands and feet