Side Effects of Medication for Benign Prostatic Hyperplasia

Men with an enlarged but noncancerous prostate gland may be treated with 5-alpha-reductase inhibitors such as the drugs finasteride (Proscar®) or dutasteride (Avodart®). Side effects of these drugs may include problems with sexual desire or erections, or breast enlargement or tenderness.

Other drugs commonly used to treat benign prostatic hyperplasia are the alpha blockers, such as terazosin (Hytrin), doxazosin (Cardura®), tamsulosin (Flomax®), or alfuzosin (Uroxatral®). Side effects of these drugs may include excessive drops in blood pressure, dizziness, swelling of the ankles, drowsiness, or retrograde ejaculation (ejaculation of sperm back toward the bladder instead of out through the penis).

Individuals with bladder obstruction are typically advised to avoid narcotic drugs or other drugs that, as a possible side effect, make it more difficult for the bladder to contract and expel urine. Speak with your physician if you are prescribed these types of drugs and are concerned about taking them.